Le laboratoire du sommeil, CHU de Grenoble

Clin Univ. de physiologie, sommeil et exercice

Contact:
Jean-Louis Pépin
Position:
Responsible
Address:
CS 10217, 38043
City:
Grenoble
Country:
France
Phone:
+33 476 765 516
Fax:
+33 476 765 586
Contact E-mail:
Research Domain
  • Clinical
  • Basic Human
Keywords
  • Others
  • Sleep and Medical Disorders
  • Epidemiology of Sleep
  • Sleep and Body Functions (Cardio-Respiratory, Thermoregulation/Metabolism, Endocrine)
  • Sleep Physiology-Neurophysiology in Human
  • Behavioural Sleep Disorders

Laboratory description

HP2 : Hypoxia ; Pathophysiology, INSERM U 1042 :
We have developed an original research project on cardiovascular consequences in intermittent hypoxia and sleep apnea using both animal, translational and clinical research. We are addressing general adaptations to hypoxia, not only during sleep but also during exercise. This is specifically the case regarding interactions between muscle, adipose tissue, brain and hypoxia. The structure of the laboratory and the scientific project are based on 4 teams, 2 on animal research (one on Vascular remodelling and atherosclerosis, the other one on Adaptation to chronic intermittent hypoxia: HIF-1 and its target genes) and 2 on translational and clinical research (one on sleep apnea and hypoxia, the other one on exercise and hypoxia).


Additional Descriptors, Keywords

Hypoxie-physiology
Sleep and exercise

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