Sleep Disorders Center, Institute of Psychiatry an, Institute of Psychiatry and Neurology

Department of Clinical Neurophysiology

Contact:
Wojciech Jernajczyk
Position:
Head of the Department
Address:
Sobieskiego 9, 02-957
City:
Warsaw
Country:
Poland
Phone:
+48 22 4582-713
Fax:
+48 22 4582-817
Contact E-mail:
Research Domain
Keywords

Laboratory description

Institute of Psychiatry and Neurology is one of the bigest psychiatric and neurological hospitals in Poland. It facilitates comprehensive diagnostic and treatment services of all sleep disorders. It is national reference center for narcolepsy and central hypersomnias and member of the European Narcolepsy Network and European Insomnia Network.


Technical Capabilities and areas of expertise

Four EEG systems (Elmiko, Poland), including one system for high density EEG/EP/ERP recordings (Neuroscan, USA)
Three PSG systems, including two systems with option for ambulatory PSG (Grass Telefactor, USA)
Three systems for sleep apnea screening (Embletta/ResMed, USA and Watch-PAT, Itamar Medical, Israel)
Nine actigraphic devices (Actiwatch, CamNtech, UK) for sleep/wake rhythm monitoring
Three actigraphic devices for RLS/PLMS diagnostics (PAM-RL, Philips Respironics, USA)


Additional Descriptors, Keywords

Areas of research interest:
sleep in patients with mental disorders
effects of antidepressants, antipsychotics and hypnotics on sleep EEG
pharmaco-EEG
alcohol and sleep
primary insomnia
narcolepsy
restless legs syndrome
circadian sleep disorders
parasomnias and epilepsy


Selected Publications in the 5 past years:

Sleep as a biomarker for depression. Wichniak A, Wierzbicka A, Jernajczyk W. Int Rev Psychiatry. 2013 Oct;25(5):632-45.

Cytokines, sleep and wakefulness regulation, and general health: a commentary to the review “The influence of cytokines on wakefulness regulation”. Wichniak A, Jarema M.
Psychiatr Danub. 2012;24(2):127-9.

Sleep and Antidepressant Treatment. Wichniak A, Wierzbicka A, Jernajczyk W. Curr Pharm Des. 2012;18(36):5802-17.

Patients with insomnia and subthreshold depression show marked worsening of insomnia after discontinuation of sleep promoting medication. Wichniak A, Wierzbicka A, Jernajczyk W.
Prog Neuropsychopharmacol Biol Psychiatry. 2011;35(7):1671-6.

Actigraphic monitoring of activity and rest in schizophrenic patients treated with olanzapine or risperidone. Wichniak A, Skowerska A, Chojnacka-Wójtowicz J, Tafliński T, Wierzbicka A, Jernajczyk W, Jarema M. J Psychiatr Res. 2011;45(10):1381-6.

REM sleep behaviour disorder in narcolepsy.
Wierzbicka A, Wichniak A, Waliniowska E, Czasak K, Musińska I, Szatkowska E, Ryglewicz D, Jernajczyk W. Neurol Neurochir Pol. 2009;43(5):421-7.

Neurophysiological examinations in narcolepsy.
Wierzbicka A, Wichniak A, Czasak K, Musińska I, Jakubczyk T, Sek A, Jernajczyk W. Przegl Lek. 2010;67(9):726-8. Review. Polish.

Sleep disorderd breathing and recurrence of cerebrovascular events, case-fatality, and functional outcome in patients with ischemic stroke or transient ischemic attack. Rola R, Jarosz H, Wierzbicka A, Wichniak A, Richter P, Ryglewicz D, Jernajczyk W. J Physiol Pharmacol. 2008;59 Suppl 6:615-21.

Sleep related breathing disorders in patients with ischemic stroke and transient ischemic attacks: respiratory and clinical correlations. Rola R, Wierzbicka A, Wichniak A, Jernajczyk W, Richter P, Ryglewicz D. J Physiol Pharmacol. 2007;58 Suppl 5(Pt 2):575-82.

The effectiveness of treatment with trazodone in patients with primary insomnia without and with prior history of hypnotics use.
Wichniak A, Wierzbicka A, Sobańska A, Szatkowska E, Czasak K, Musińska I, Jernajczyk W. Pol Merkur Lekarski. 2007;23(133):41-6. Polish.


Key Publications of the Laboratory:

Sleep as a biomarker for depression. Wichniak A, Wierzbicka A, Jernajczyk W. Int Rev Psychiatry. 2013 Oct;25(5):632-45.

Sleep and Antidepressant Treatment. Wichniak A, Wierzbicka A, Jernajczyk W. Curr Pharm Des. 2012 Jun 6. [Epub ahead of print]
PMID: 22681161

Patients with insomnia and subthreshold depression show marked worsening of insomnia after discontinuation of sleep promoting medication. Wichniak A, Wierzbicka A, Jernajczyk W.
Prog Neuropsychopharmacol Biol Psychiatry. 2011;35(7):1671-6.

Actigraphic monitoring of activity and rest in schizophrenic patients treated with olanzapine or risperidone. Wichniak A, Skowerska A, Chojnacka-Wójtowicz J, Tafliński T, Wierzbicka A, Jernajczyk W, Jarema M. J Psychiatr Res. 2011;45(10):1381-6.

Sleep disorderd breathing and recurrence of cerebrovascular events, case-fatality, and functional outcome in patients with ischemic stroke or transient ischemic attack. Rola R, Jarosz H, Wierzbicka A, Wichniak A, Richter P, Ryglewicz D, Jernajczyk W. J Physiol Pharmacol. 2008;59 Suppl 6:615-21.


Current/Completed Grants (past 5 years):

2005-2008 Research Grant from Polish Ministry of Science and Higher Education number 2 P05B 124 29 „Functioning, circadian rhythm, activity level and daytime sleepiness in patients with schizophrenia in the first year of the treatment.”

2005-2008 Research Grant from Polish Ministry of Science and Higher Education 2 P05B 195 29 „Sleep disordered breathing in patients with stroke.”

2008-2010 Statutory research grant from Institute of Psychiatry and Neurology 09/2008 „Prevalence of periodic leg movements in sleep and restless legs syndrome in patients with schizophrenia – implications for assessment of dopaminergic activity”.

2011-214 Research Grant from Polish National
Science Center (NCN) number 4650/B/P01/2011/40
“Cognitive neurorehabilitation in patients with schizophrenia – assessment of its effects on cognitive and social functioning, quality of life and severity of illness”


Other laboratory Members

Title:  PhD MD

Name:  Adam Wichniak

Position:  associate professor of psychiatry, and vice-head of the Third Department of Psychiatry

Email:  wichniak@ipin.edu.pl

Title:  MD

Name:  Aleksandra Wierzbicka

Position:  specialist in neurology, epilepsy and electroencephalography

Email:  wierzbic@ipin.edu.pl


Collaborations

Title:  MD

Name:  Peter Geisler

Position:  Head of the Sleep Disorders Center

Institution:  Sleep Didorders Center, University of Regensburg

Title:  PhD MD

Name:  Elisabeth Friess

Position:  Head of RG Genetics of Human Sleep

Institution:  Max Planck Institute of Psychiatry

Title:  PhD MD

Name:  Axel Steiger

Position:  Head of RG Endocrinology of Sleep

Institution:  Max Planck Institute of Psychiatry

Title:  PhD MD

Name:  Paul Linkowski

Position:  Head of the Department

Institution:  University Hospital Erasme, Sleep Laboratory, Department of Psychiatry

Title:  PhD MD

Name:  Mehdi Tafti

Position:  Head of RG Genetics of sleep and the sleep EEG

Institution:  Center for Integrative Genomics, Université de Lausanne

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