UR2NF - Neuropsychology and Functional Neuroimagin, Université Libre de Bruxelles (ULB)

Faculty of Psychological Sciences

Contact:
Philippe Peigneux
Position:
Professor
Address:
CP191 Av F Roosevelt,
City:
Bruxelles
Country:
Belgium
Phone:
+32 2 650 4581/2631
Fax:
+32 2 650 2209
Research Domain
  • Basic Human
Keywords
  • Learning, Memory, Cognition
  • Sleep and Medical Disorders
  • Sleep and Ageing
  • Sleep and Body Functions (Cardio-Respiratory, Thermoregulation/Metabolism, Endocrine)
  • Sleep Physiology-Neurophysiology in Human
  • Biological Rhythms
  • Behavioural Sleep Disorders
  • Neurological Sleep Disorders

Laboratory description

The current research conducted at the Neuropsychology and Functional Neuroimaging Research Group [UR2NF ] is experimental in nature while extending to the clinical and developmental domains. Our research activities mainly but not exclusively focus on investigating the relationships between sleep, learning and memory consolidation processes, and in a wider perspective, the interrelationships between cognitive processes and vigilance states. This includes sleep and biological rhythms in both healthy and pathological conditions as our areas of research cover sleep and circadian disorders, children development and healthy ageing, disorders of consciousness (coma, vegetative state), developmental (e.g. ADHD) and epilepsy syndromes, other neurological disorders and pathological ageing (Multiple Sclerosis, Parkinson, Alzheimer disease…). We specifically focus on the processes by which novel representations are created in memory and the mechanisms by which information is consolidated into long-term memory. We are also interested in the understanding and investigation of major neuropsychological syndromes. Given our expertise in functional neuroimaging techniques, UR2NF collaborates with many local and international groups on various research projects. These studies are primarily conducted using behavioural protocols as well as advanced brain imaging techniques, e.g. functional magnetic resonance imaging (fMRI), electroencephalography (EEG), magnetoencephalography (MEG), transcranial direct current stimulation (TDCs) and near-infrared spectroscopy (NIRS). For a full list of our members and publications, see http://crcn.ulb.ac.be/lab/ur2nf/


Technical Capabilities and areas of expertise

Neuropsychology, Sleep Deprivation, Polysomnography (PSG), Positon Emission Tomography (PET), functional Magnetic Resonance Imaging (fMRI), Magnetoencephalography (MEG), Near Infrared Spectroscopy (NIRS), eyetracking


Additional Descriptors, Keywords

neuroimaging, memory consolidation, cognition


Selected Publications in the 5 past years:

Please see http://crcn.ulb.ac.be/lab/ur2nf/ for our articles and full text access


Key Publications of the Laboratory:

Please see http://crcn.ulb.ac.be/lab/ur2nf/ for our articles and full text access


Current/Completed Grants (past 5 years):

Ongoing research support

1/01/2018 – 31/12/2021 Excellence of Science (EOS) Research Project O017418F – MEMODYN: “The journey of a memory: dynamics of learning and consolidation in maturation and ageing” – Project Leader Philippe PEIGNEUX (ULB), Partner Universities ULG, UGhent and KULeuven
1/05/2016 – 1/05/2021 Fonds Erasme Excellence in Research Project “Dysregulation of cerebral perfusion in sepsis-associated brain dysfunction: from bench to bedside” – Project Leader Jacques CRESTEUR (ULB-Erasme), Faculty of Psychology Partner Philippe PEIGNEUX (ULB)
1/10/2016 – 31/09/2019 Circuit-based deconstruction of Attention Deficit and Hyperactive Disorder with optogenetic Light control (Partner) Individual Fellowship Marie Sklodowska Curie Action – Patricia BONNAVION (ULB), Serge SCHIFFMANN (ULB) and Philippe PEIGNEUX (ULB)
1/01/2015 – 31/12/2018 Hypnos’ healing powers: The role of sleep in fear generalization, (Co-promotor) FWO grant number G.0760.15N. Tom BECKERS (KUL), Yannick BODEZ (KUL) and Philippe PEIGNEUX (ULB)
1/10/2014 – 31/12/2019 Research Logistic Collaborator position (Co-promotor). Investigation with magnetoencephalography of major human brain systems and their alteration in brain disorders. Serge GOLDMAN, Philippe PEIGNEUX, Patrick VAN BOGAERT, Xavier DE TIÈGE

Completed research support

1/010/2014 – 31/12/2017 WBI-CAPES Projet N°7 (main promotor). A dose-response study of the combined psychophysiological effects of acute sleep deprivation and hypoxia. Co-promotors Marco Túlio de Mello, Psychobiology DepartmentUniversidade Federal de São Paulo, Nathalie Pattyn (Unité VIPER, Ecole Royale Militaire) and Olivier Mairesse (VUB).
1/07/2013 – 30/06/2016 FQRNT Research Project: Cortical localization of oscillatory activities and functional connectivity during sleep in aging: a comprehensive approach combining electroencephalography (EEG) and magnetoencephalograhy (MEG). Promotors J-M Lina (LATIS – Laboratoire de Traitement de l’Information des Signaux, ETS et PhysNum laboratory at the Centre de Recherche Mathématique, Université de Montréal), J. Carrier (Sleep laboratory, Institut Universitaire de Gériatrie de Montréal), P. Jolicoeur (Centre MEG of the Université de Montréal), I. Timofeev (Université Laval, Québec), P. Peigneux (ULB).
1/07/2013 – 30/06/2017 FNRS Research project (PDR) 14626883 (principal promotor): Within-sleep stimulation of brain activity and formation of novel memories.
1/06/2012 – 30/05/2017 National Institute of Health (NIH) R01 HD033487-15 project (consultant) Neuromaturational Delays in Iron Deficient Anemic Infants. Main promotor Prof Dr Patricio Peirano (INTA, University of Chile) in collaboration with Prof Betsy Lozoff and Prof Beatriz Luna (University of Michigan at Ann Arbor)
1/10/2013 – 30/09/2015 Brains Back to Brussels project (P. Peigneux promotor) awarded to Dr Rachel Leproult: A neurophysiological, cognitive and biological investigation of the effects of bedtime extension as an intervention to counteract the adverse effects of chronic sleep loss
1/01/2012 – 31/12/2015 FRSM project 7020836 (principal promotor): Memory consolidation and brain plasticity processes in normal and pathological ageing. Other promotors Prof P Van Boagert (LCFC [Laboratoire de Cartographie Fonctionnelle du Cerveau] et Département de Neurologie Pédiatrique, ULB) and J-C Bier (Faculté de Médecine, ULB)
1/10/2010 – 30/09/2015 Action de Recherche Concertée [ARC] project (co-principal promotor) Pathophysiology of brain plasticity processes in memory consolidation. Other promotors P. Van Bogeart (LCFC [Laboratoire de Cartographie Fonctionnelle du Cerveau] et Département de Neurologie Pédiatrique, ULB), A. Kerchove d’Exaerde (Laboratoire de Neurophysiologie, Faculté de Médecine, ULB)
1/01/2012 – 31/12/2013 FNRS Large Equipment and Infrastructure Project 8833807 (Coordinator and Principal Investigator): IP-CONE Integrated Projects in Cognition and Neurosciences. Other promotors Profs. Alain Content, Arnaud Destrebecqz, Axel Cleeremans, Cécile Colin, Jacqueline Leybaert, Régine Kolinsky, Wim Gevers (CRCN – Centre de Recherche Cognition et Neuroscience, ULB)
1/10/2010 – 30/09/2013 Brains Back to Brussels project (P. Peigneux promotor) awarded to Dr Rachel Leproult, formerly at Chicago University: A neurophysiological, cognitive and biological investigation of the effects of bedtime extension as an intervention to counteract the adverse effects of chronic sleep loss.


Other laboratory Members

Name:  Charline Urbain

Position:  Assistant Professor

Email:  curbain@ulb.ac.be

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