Sleep & Cognition, Netherlands Institute for Neuroscience

Sleep & Cognition

Contact:
Eus JW Van Someren
Position:
Prof., Head of department
Address:
Meibergdreef 47, 1105
City:
Amsterdam
Country:
Netherlands
Phone:
+31 20 566 5500
Fax:
+31 20 566 6121
Research Domain
  • Methodology / Technology
  • Clinical
  • Basic Human
Keywords
  • Instrumentation-Methodology
  • Learning, Memory, Cognition
  • Sleep and Ageing
  • Epidemiology of Sleep
  • Sleep and Body Functions (Cardio-Respiratory, Thermoregulation/Metabolism, Endocrine)
  • Sleep Physiology-Neurophysiology in Human
  • Light and Non-Classical Photoreception
  • Biological Rhythms
  • Neurological Sleep Disorders

Laboratory description

Against the background of their 24-hour rhythm, driven by the circadian clock of the brain, sleep and wakefulness show a mutual dependency. The Sleep & Cognition group investigates how sleep affects brain function during subsequent wakefulness, and how experiences during wakefulness affect subsequent sleep. We aim firstly to elucidate factors that promote and disturb sleep at the systems level, notably insomnia, and secondly to investigate the brain mechanisms involved in the favorable and disruptive effects on cognition of, respectively, sleep and sleep disturbances. We think it’s important to translate fundamental insights into applications to improve sleep, vigilance and daytime function.

Human research tools include, in addition to the standard sleep-lab, brain imaging (high-density-EEG, MEG, fMRI on 1.5, 3 and soon 7 Tesla), transcranial magnetic stimulation (TMS), eye-tracking, computerized induction and assessment of task performance. The sleep-lab has a unique setup for comfortable skin temperature clamping in humans. An arsenal of ambulatory monitoring equipment is available. A web-based assessment tool for extensive insomnia and good sleep phenotyping has resulted in a growing database of, at present, 7000 people. The tool is available for other researchers that want to cooperate.

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