- Neurological Sleep Disorders
- Sleep and Psychiatry-Personality Disorders
- Sleep and Medical Disorders
The sleep laboratory at the University Hospital of Geneva has as the main mission the diagnosis and treatment of sleep disorders.
The current research projects concern insomnia and excessive daytime sleepiness, by studying oscillatory neuronal activity.
The main techniques used for projects are EEG devices and psycho-physiological tools.
Additional Descriptors, Keywords
Attention, aging, depression, sleep apnea.
Key Publications of the Laboratory:1 Sforza E., Jouny C., Ibanez V. Time-dependent variation in cerebral and autonomic activity during periodic leg movements in sleep: implications for arousal mechanisms. Clin Neurophysiol 2002; 113: 883-891.
2 Sforza E, Jouny C, Ibanez V. Time course of arousal response during periodic leg movements in patients with periodic leg movements and restless legs syndrome. Clin Neurophysiol 2003;114:1116–24.
3 Lavoie S., De Bilbao F., Haba-rubio J., Ibanez V., Sforza E.. Influence of sleep stage and wakefulness on spectral EEG activity and heart rate variations around periodic leg movements. Clinical Neurophysiol. 2004; 115, 2236-2246.
4 Haba-Rubio J, Janssens J-P, Rochat T, Sforza E. Rapid eye movement-related disordered breathing: clinical and polysomnographic features. Chest 2005;128:3350–7.
5 Sforza E, Pichot V, Cervena K, Barthélémy J-C, Roche F. Cardiac variability and heart-rate increment as a marker of sleep fragmentation in patients with a sleep disorder: a preliminary study. Sleep 2007;30:43–51.
6 Cervena K, Espa F, Perogamvros L, Perrig S, Merica H, Ibañez V. Spectral analysis of the sleep onset period in primary insomnia. Clin Neurophysiol 2014;125:979–87.
7 Perogamvros L, Pépin J-L, Thorens G, Mégevand P, Claudel E, Espa F, et al. Baclofen-Associated Onset of Central Sleep Apnea in Alcohol Use Disorder: A Case Report. Respiration 2015;90:507–11.
Name: Jean-Louis Pepin
Position: physician (pneumologist)
Institution: University Hospital of Grenoble
Name: Natalie Darchia
Position: Professor, Research senior
Institution: University of Georgia