Physiopathology of the neuronal networks of the sl, UMR 5292 CNRS/U1028 INSERM

Team "Sleep"

Contact:
Pierre-Hervé Luppi
Position:
DR1 CNRS
Address:
7, Rue Guillaume Paradin, 69372
City:
Lyon
Country:
France
Phone:
+33478771040
Fax:
+33478771022
Research Domain
  • Basic Animal

Laboratory description

11 INSERM/CNRS researchers,
1 University researcher,
7 technical staff,
11 PhD students

Areas of research:

• Neuronal mechanisms of the sleep-wake cycle: identification of brain structures and their interconnections involved in the genesis, maintenance and homeostasis of sleep, especially paradoxical (REM) sleep in normal conditions and animal models of sleep disorders.

• The function of sleep, particularly the role of paradoxical sleep in memory consolidation: multi-level (behavior, network, cellular) investigation of the beneficial role of sleep in learning and memory.

• The impact of sleep on mood regulation and depression.


Additional Descriptors, Keywords

• Brain mechanisms underlying PS onset, maintenance and homeostasis (P.H. Luppi, P. Fort, D. Gervasoni)
• Brainstem mechanisms of PS atonia and REM-behavior disorder (P.H. Luppi, P. Fort)
• Hypothalamic regulation of paradoxical sleep and narcolepsy (C. Peyron, P. Fort)
• Role of sleep in learning and memory, hippocampal sleep-dependent plasticity (G. Malleret, P.Salin, R.Parmentier)
• Physio-pathology of sleep and learning in an animal model of depression (J-M Vaugeois, M. El Yacoubi)
• Anatomical substrate of depression and addiction (A.Bérod)

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