Sleep Science Friday: Respiratory Physiology and updates from the British Sleep Society—with Professor Joerg Steier

Sleep Science Friday

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Sleep Science Friday: Respiratory Physiology and updates from the British Sleep Society—with Professor Joerg Steier

4 December 2020

During sleep, the body goes through physiologic changes, including those related to breathing, such as decreased muscle activity in the upper airway muscles. In healthy individuals, this isn’t a problem; but in some individuals with certain structural/anatomic features (e.g., thicker neck, overweight, etc.), this relaxation can lead to narrowing in the upper airways affecting the ability to sleep and can lead to snoring and sleep apnea. Our breathing is also under the control of a network of respiratory-related neurons. When approaching a patient with sleep-disordered breathing, we should also consider the individual variability in respiratory physiology (Bosi M et al., 2020).

Today, Dr. Lyudmila Korostovtseva (a cardiologist and Research Fellow at the Sleep Medicine Laboratory at the V.A. Almazov North-West Federal Medical Research Centre, in St Petersburg) talked with our guest, Professor Joerg Steier. Professor Steier is the President of the British Sleep Society, Professor of Respiratory and Sleep Medicine at King’s College London, and an expert in respiratory physiology.

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The full interview is 53:50 min (see highlights on the introduction of Professor Steier and respiratory physiology; on transcutaneous electrical stimulation for obstructive sleep apnea; and the narcolepsy update).

We discussed with Professor Steier about respiratory physiology [at 01:58], diagnosing and phenotyping sleep-disordered breathing [at 04:19], and treatment options in obstructive sleep apnea [at 05:40], as well as ways to overcome low adherence [at 10:00], and other difficulties associated with treating sleep-disordered breathing [at 15:17].

Professor Steier shared with us his personal experience in treating patients with sleep-disordered breathing, as well as implementing recent developments in this field, particularly non-CPAP therapy, such as the novel technique of transcutaneous electrical stimulation [at 19:17 to 37:15]. Electrical stimulation methods are rather novel in treating obstructive sleep apnea (Ratneswaran D et al., 2020). Hypoglossal nerve stimulation was approved in 2014 by the FDA to treat obstructive sleep apnea and is an invasive procedure as it requires surgery and an implant. Transcutaneous electrical stimulation was developed as a potential non-invasive alternative. Professor Steier and his colleagues have been working on developing this technique and are currently running a randomized controlled trial (TESLA-home) in the UK.

Professor Steier also gave some insights into sleep-related healthcare management during the COVID-19 pandemic [at 45:46] based on the personal experiences and statements released by the British Sleep Society (such as the audit on the Impact of COVID-19 on UK Sleep Services, and a statement on sleep-related advice during the coronavirus pandemic, for further details see here).

Last but not least, Professor Steier gave us the latest news from the British Sleep Society, including the launch of the BSS Strategic Plan today (at 42:15) and the BSS Narcolepsy Webinar (at 37:54). The Narcolepsy Webinar was held this afternoon (4 December 2020) and will be recorded and stored on the BSS website.

For additional reading and recent publications from professor J. Steier and the BSS: 

Electrical stimulation in obstructive sleep apnea:

On Sleep Apnea Phenotyping:

The impact of COVID-19 on sleep:

For additional reading and other latest publication on related topics:

On electrical stimulation:

Sleep apnea phenotyping

For similar ESRS articles on sleep-disordered breathing, COVID-19 and sleep—see past Sleep Science Fridays:

Have a great weekend everyone and sleep sound!

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December 10, 2020
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